Johns Hopkins University – Homewood Campus – (410-516-5250/office phone)
Thursday, February 22, 2007
3:45 p.m.
Johns Hopkins University
Department of Neurology
“Cerebellar Function in Verbal Working Memory”
Neuroimaging has demonstrated that cerebellar activations that are observed during cognitive performance are tightly coupled with those observed in neocortical areas. These data are consistent with patient studies indicating that cerebellar damage can impair cognitive function. The present talk will explain how knowledge of cerebro-cerebellar circuitry may help to interpret patterns of functional cerebellar activations that are consistently found during a basic cognitive process, verbal working memory. A model of cerebro-cerebellar circuitry in verbal working memory is presented and tested with functional MRI and transcranial magnetic stimulation experiments. The results suggest that cerebellar activations during verbal working memory can be interpreted within the theoretical framework of the phonological loop as proposed by Baddeley.
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